Other mutated cancer genes included those involved in Wnt signaling (APC, AMER1), mitogen signaling (KRAS, BRAF), epigenetic modification (ARID1A, ARID2, DNMT3A, NCOA3) and DNA repair (RAD50, BRIP1, ERCC5, RECQL4). The gene discussed is BRIP1; the disease is cancer.