Other mutated cancer genes included those involved in Wnt signaling (APC, AMER1), mitogen signaling (KRAS, BRAF), epigenetic modification (ARID1A, ARID2, DNMT3A, NCOA3) and DNA repair (RAD50, BRIP1, ERCC5, RECQL4). This evidence concerns the gene ERCC5 and cancer.