INS and type 2 diabetes mellitus: Notably, data from DROPOUT studies (n = 433 and n = 1,456) (25, 26) in insulin-naive type 2 diabetes patients in Turkey revealed association of premixed insulin treatment with better patient compliance compared to basal-bolus treatment in terms of dose-skipping (19 vs. 52%) and not using insulin for more than a day (22.7 and 61.3%) (25), while in terms of higher treatment adherence (75 vs. 62.8%) compared to basal insulin (26).