For example, miR-9-5p can target PAK4 to repress the proliferation and inhibit the apoptosis of colon cancer cells (Wang M. et al., 2019); in cervical cancer, miR-9-5p can regulate the angiogenesis and radiosensitivity of cervical cancer cells by targeting SOCS5 (Wei et al., 2019). This evidence concerns the gene PAK4 and malignant colon neoplasm.