IL1B and nervous system disorder: Several oxidative stress and inflammatory markers are raised in the serum of patients with HD, including CRP, GM-CSF, TNF, IL-1β, IL-6 and IL-8, strongly suggesting an inflammatory phenotype in this neurological disorder (Björkqvist et al., 2008; Sánchez-López et al., 2012; Chang et al., 2015; Politis et al., 2015; Rodrigues et al., 2016).