The MIF levels in pancreatic tissue and serum were increased in l-arginine-induced AP (ARG-AP) in mice (Ohkawara et al., 2017) and their expression was up-regulated in the intrahepatic bile duct cells in a sodium taurocholate-induced AP (STC-AP) in rats (Wang et al., 2019). This evidence concerns the gene MIF and alkaline phosphatase measurement.