While inhibition of miR-301b abolished MIF-induced suppression of NR3C2 in vitro, Mif−/− mice were associated with reduced metastasis and improved survival in a pancreatic cancer mouse model (LSL-KrasG12D, LSL-Trp53R172H/+, Pdx-1-Cre) in vivo. This evidence concerns the gene NR3C2 and familial pancreatic carcinoma.