MIF and cancer: MIF is now known to have a pivotal role in metabolic (Morrison and Kleemann, 2015), acute inflammatory (Hertelendy et al., 2018), autoimmune (Greven et al., 2010) and infectious diseases (Leaver et al., 2010), and cancers (O’reilly et al., 2016) including colorectal (He et al., 2009), malignant melanoma (Oliveira et al., 2014), lung (Tomiyasu et al., 2002), breast (Tomiyasu et al., 2002), and prostate (Meyer-Siegler et al., 2002) cancers as well as glioblastomas (Munaut et al., 2002).