It is also found that circNUP98 is under the regulation of STAT3, and it functions as a sponge of miR-567 and promotes the expression of PRDX3 (an antioxidant protein, belongs to the peroxiredoxins), leading to RCC progression (Cox et al., 2009; Yu et al., 2020). Here, STAT3 is linked to renal cell carcinoma.