TLR2 and infection: Toll-like receptor 2 (TLR2) is a protein that senses pathogen molecules and develops the intracellular signaling in response to a possible infection (Beutler et al., 2006); a genetic variant that affects the functionality of this receptor could increase the risk of infections (Hawn et al., 2009; Bielinski et al., 2011; Esposito et al., 2014).