There are several classesof drugs which target malignant angiogenesis, such as anti-vascular endothelial growth factor (VEGF) antibodies, proteins with binding portions for the extracellular domains of human VEGF receptors 1 and 2, which will retain tumor-released VEGF (a VEGF trap: aflibercept, for example), or protein kinase inhibitors which target angiogenic, stromal and oncogenic receptor tyrosine kinase (RTK) (Stivarga, 2020; Zaltrap, 2020). The gene discussed is VEGFA; the disease is neoplasm.