CALB1 and Alzheimer disease: By contrast, a loss of Calb-ir neurons has been reported in the hippocampus (McLachlan et al., 1987; Stefanits et al., 2014), cerebral cortex (Ichimiya et al., 1988) and nucleus basalis of Meynert (Ichimiya et al., 1989; Riascos et al., 2011) in AD.