In addition to the above, HERV-W env is a powerful superantigen linked with demyelination in MS (Perron et al., 2001; Rolland et al., 2005), perhaps associated with molecular mimicry with myelin oligodendrocyte glycoprotein (MOG) (do Olival et al., 2013; de Luca et al., 2019). The gene discussed is ERVW-1; the disease is myeloid sarcoma.