SNCA and Parkinson disease: Interestingly, FKBP1A protein level was augmented in a 6-OHDA model of PD, as well as in brains of PD patients (reviewed by Chattopadhaya et al., 2011), and it has been shown to play a key role in α-synuclein toxicity in a rat model of PD (Caraveo et al., 2017).