ACTA1 and glioma: Among these deregulated proteins, the actin α1 skeletal muscle (Acta1), which is implicated in cell motility, structure, and integrity, and Atp6v1e2, an ATPase H+ transporter essential for catabolic processes, are both known to be prognosis markers in gliomas as they are involved in invasion and motility of cancer cells (Yang et al., 2012; Ohtaki et al., 2017).