Researches showed editing role in the pathogenesis of cancer and indicated its relation with mediators such as tumour necrosis factor-α (TNF-α), soluble TNF-related apoptosis-inducing ligand (sTRAIL), interleukin-6 (IL-6), pentraxin-3 (PTX-3), procalcitonin (PCT), and Creactive protein (CRP) levels [5], [6], [7], [8], [9], [10], [11]. The gene discussed is TNF; the disease is cancer.