According to this, very similarly, NF-κB and TNF-α showed very high positive correlation with tumour grade (respectively r=0.910, p<0.001 and r=0.912, p<0.001), high positive correlation with the presence of HER2 (both r=0.774, p<0.001) and metastasis (respectively r=0.857, p<0.001 and r=0.856, p<0.001), high negative correlation with the presence of ER (both r=-0.839, p<0.001) and PR (respectively r=-0.866, p<0.001 and r=-0.865, p<0.001). The gene discussed is ESR1; the disease is neoplasm.