BMI, body mass index; CA-15.3, cancer antigen 15.3; CA-19.9, cancer antigen 19.9; CEA, carcinoembryonic antigen; NF-κB, nuclear factor kappa-B; sTRAIL, soluble tumour necrosis factor (TNF)-related apoptosis-inducing ligand; TNF-α, tumour necrosis factor-α; IL-6, interleukin 6; PCT, procalcitonin; PTX-3, pentraxin 3; CRP, C-reactive protein. The gene discussed is CEACAM5; the disease is cancer.