Our results of rs1800587 of IL-1α and rs1143634 of IL-1 polymorphisms, consistent with the findings of Noponen-Hietala et al. [16] did not find an association between rs1800587 of IL-1α and rs1143634 of IL-1 polymorphisms and IDD. This evidence concerns the gene IL1A and intervertebral disk degenerative disorder.