Other immunohistochemical stains performed to rule out other spindle-cell lesions (spindle cell carcinoma, desmoplastic melanoma, dermatofibrosarcoma protuberans, nodular fasciitis, malignant peripheral nerve sheath tumor, spindle cell atypical fibroxanthoma, fibrosarcoma, synovial sarcoma, and vascular tumors) include EMA, CD34, CD117, CEA, HMB45, Mart-1, Melan A and CK7; all of them are negative in LMS.2 The gene discussed is PMEL; the disease is vascular neoplasm.