Levels of TIMP-1 in subjectively healthy controls earlier reported from our department are 92 ng/mL (range 80–103).23 MMP-9 had a mean value of 82 ng/mL in the type 1 diabetes patients (95% CI: 64–99) as compared to 53 ng/mL (range 43–85), in healthy controls.23 Patient characteristics and values for all analysed plasma markers are shown in Table 1 and pathological complications and presence of diabetic neuropathy are shown in Table 2. This evidence concerns the gene TIMP1 and diabetic neuropathy.