VEGFA and cancer: On the other hand, our results demonstrated that similar to antibacterial results, in cytotoxicity tests, apoptosis, and expression of genes responsible for cancer cell metastasis and angiogenesis, in both nanoparticles (30 and 60 nm) with increased concentration led to decreased survival, expression of MMP-2 and VEGF genes and also increased apoptosis in 4T1 cancer cells.