CTTN and B-cell chronic lymphocytic leukemia: Recent studies have demonstrated cortactin overexpression to be related to disease progression and bad prognosis in different hematological malignancies such as B-CLL (Gattazzo et al 2014), non-Hodgkin B-cell lymphomas (Pizzi et al., 2019) and B-cell ALL (Velázquez-Avila et al., 2019).