CTTN and precursor B-cell acute lymphoblastic leukemia: The significant parameters in univariate analysis were evaluated in multivariate analysis which revealed that high cortactin and HS1 gene expression were considered as significant risk predictors of B-ALL relapse (P=0.005, OR=1.428, CI [1.175-1.783]; P=0.003, OR= 1.078, CI [1.025-1.134]; respectively) and high probability of deaths (P= 0.041, OR = 1.092, CI [1.002-1.046]; and P=0.005, OR= 1.071, CI [1.013-1,041]; respectively) (Table 6) (Figure3a, 3b).