In addition to the above autoantibodies targeting extracellular proteins, autoantibodies against intracellular antigens, such as anti‐titin, anti‐ryanodine receptor and anti‐cortactin antibodies, are less likely pathogenetic for MG but markers for MG characteristics, such as disease severity, the presence of thymoma and myopathy.8, 22. This evidence concerns the gene TTN and thymoma.