COL1A1 and head and neck cancer: We analyzed the TCGA and GTEx project databases using the Human Protein Atlas (https://www.proteinatlas.org/about) and GEPIA255 (Supplementary Figure S1A and S1B) tools, identifying cancers expressing high levels of COL1A1 and COL1A2. Head and neck cancer, breast cancer, and sarcomas are all malignancies with increased type I collagen expression.