As enlightened by a recent study [22] on a cohort of non-demented patients, including ALS, ALS-bi, and ALS-ci cases, the presence of verbal fluency deficits appears to be highly predictive for TDP-43 deposition in specific brain areas (Broadmann area 9, 41, 44). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.