Comparative RNA expression analysis of genes associated with receptor status in Study biopsy #2: ESR1 (ER), PGR (PR), ERBB2 (HER2) and AR, showed high RNA expression in relation to basal intrinsic subtypes from The Cancer Genome Atlas (TCGA) primary breast cancer cohort (Fig. 4a). The gene discussed is ESR1; the disease is breast carcinoma.