There are abundant reports of exacerbation of TGFBI-related corneal dystrophies, including GCD2 or GCD1 with deposits, following corneal trauma such as laser-assisted in situ keratomileusis28,29, LASEK, photorefractive keratectomy, and refractive keratotomy4,30,31. This evidence concerns the gene TGFBI and corneal dystrophy.