Note that these significantly different genes were related mainly to positive regulation of the acute inflammatory response (GO:0002675), the TGF-beta signaling pathway (hsa04350), regulation of the T cell receptor signaling pathway (GO:0050856), the nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184), and positive regulation of vascular endothelial growth factor production (GO:0010575) and proteoglycans in cancer (Fig. 8b). Here, VEGFA is linked to cancer.