To understand the events that occur in TICs upon inhibition of Met and FGFR1, we performed gene expression profiling by RNA-Sequencing of RNA prepared from tumourspheres from three independent MMTV-Metmt;Trp53fl/+;Cre-derived spindloid tumour cell lines (A1005, A1129 and A1471) following treatment with Met or FGFR inhibitor alone (Crizotinib or PD173074, respectively), or in combination for 24 h. The gene discussed is FGFR1; the disease is neoplasm.