Within community 2, we also identified increased expression of regulators of cell proliferation (CENPE, MKI67, TOP2A, UBE2C, guanine), cancer, and pluripotency (DNMT3B, DPPA4, MYC, POU5F1, CRABP2) (Fig. 4c–e). The gene discussed is MKI67; the disease is cancer.