However, whereas the serum levels of aspartate aminotransferase (AST) and glutamyl transpeptidase (GGT), together with the PT were significantly increased in the S. japonicum infection-induced liver cirrhosis group, the total protein, and albumin serum levels were significantly decreased in the same group, in comparison with those in the control group (Table 1; at least P < 0.05). The gene discussed is F2; the disease is cirrhosis of liver.