LRRK2 and Cognitive impairment: After adjusting age, disease duration and schooling year, we found that males with LRRK2 G2385R carriers showed lower risk in cognitive impairment (OR = 0.301, p = 0.003) as compared with males without LRRK2 G2385R non-carriers (Table 2) and the association remained significant after Bonferroni correction.