We suspect, however, that this is a limitation that may disproportionately affect GDT rather than BAT + GDT, as quality measures such as MLWHF and HF markers such as NT-proBNP and 6MHW show clear benefits associated with BAT + GDT (relative to GDT alone) in the BeAT-HF clinical trial. Here, NPPB is linked to hydrops fetalis.