The RE in C9orf72 gene, the most frequent pathogenic mutation in our sample (Table 2) and in general in the ALS/FTD continuum in Europe [47], was associated with every phenotype of the ALS/FTD continuum and was evenly distributed in the two subgroups of fALS (Table 2). The gene discussed is C9orf72; the disease is frontotemporal dementia.