The role of eosinophils in the pathogenesis of ILD has not been comprehensively understood yet: cytokines involved in eosinophil activation like Interleukin(IL)-4, IL-5, IL-13 or IL-33 also play a major role in the pathophysiology of IPF and SSCILD [10, 35, 38, 39]. This evidence concerns the gene IL33 and interstitial lung disease.