Moreover, fatty acid binding protein 7 (FABP7), a marker of immature enteric glia, was significantly upregulated in the myenteric plexus and resulted in a higher ratio of FABP7 to S100 calcium-binding protein B (S100B) expression as compared to controls, signifying a higher proportion of immature EGCs in the ganglionic bowel of HSCR patients [55]. The gene discussed is S100B; the disease is Hirschsprung disease.