GALGT2 overexpression can protect both wild type and dystrophic mouse skeletal myofibers from injury in mouse models, including the mdx model for DMD, the dyW model for Congenital Muscular Dystrophy type 1A (MDC1A), the Sgca model for Limb Girdle Muscular Dystrophy 2D (LGMD2D), and the FKRPP448L model for Limb Girdle Muscular Dystrophy 2I (LGMD2I) [35–38]. Here, B4GALNT2 is linked to Duchenne muscular dystrophy.