LPA and coronary artery disorder: Two variants (rs10455872 and rs3798220) are both highly associated with increased plasma Lp(a), reduced LPA copy number (i.e. reduced KIV2 repeats), and smaller Lp(a) lipoprotein size—associated with an odds ratio for coronary artery disease of 1.5 for one variant and 2.57 for two or more variants.40