Furthermore, compared with 800CW-TATE-injected H69 xenograft bearing mice, IRDye800CW carboxylate-injected H69 xenografted mice had 83.4  ±  4.8% reduction, and SSTR2 negative CH-157MN xenograft bearing mice showed a reduction of 78.4  ±  4.8% tumor uptake. This evidence concerns the gene SSTR2 and neoplasm.