We then examined TMEM180 mRNA expression changes between schizophrenia cases and controls using the expression data from Sun et al. (Chinese sample).35 Consistent with the prediction of integrative analyses, we found that TMEM180 was significantly down-regulated in the blood samples of schizophrenia cases compared with controls (P = 8.63 × 10–4) (figure 1b), with an effect size (Cohen’s d) of 1.22. Here, SLC68A1 is linked to schizophrenia.