SLC68A1 and schizophrenia: We further explored TMEM180 mRNA expression in brains of schizophrenia cases and controls using expression data from the PsychENCODE.41 Again, TMEM180 was significantly down-regulated in the brains of schizophrenia cases compared with controls (P = 1.87 × 10–5), with an effect size (Cohen’s d) of 0.906.