AHR and colitis: In this context, Tent et al. reported that plant mdo-miR-7267-3p repressed ycnE expression in Lactobacillus rhamnosus, upregulating the production of I3A and leading to increased IL-22 production [by activating aryl hydrocarbon receptor (AHR) pathway in lymphocytes], which in turn strengthened gut barrier and improved colitis in mice (125).