IGF1 and hepatocellular carcinoma: Overexpression of IGF-associated miRNAs namely miR-30a-3p, miR-155, miR-199a-3p, and miR-486-5p has important roles in different conditions such as preeclampsia, hepatocellular carcinoma, estrogen-mediated autophagy, and congenital heart disease (El Tayebi et al., 2015; Fu et al., 2018; Niu et al., 2018; Fan et al., 2019).