IGF1R and hepatocellular carcinoma: miR-99a, miR-503, and miR-1275 contribute to the pathogenesis of polycystic ovary syndrome, coronary heart disease, and hepatocellular carcinoma by affecting IGF-1R levels (Fawzy et al., 2015; Zhu W. et al., 2018; Geng et al., 2019).