KMT2A and acute myeloid leukemia: Rearrangements of the MLL gene in AML have been associated with Alu-mediated recombination events (68–70), while the induction of AML in a xenograft mouse model for primary myelofibrosis (PMF) was attributed to unrestricted replication and subsequent viremia of murine leukemia virus (MuLV), potentially due to a paracrine mechanism in peptide mass fingerprinting (PMF) (71).