ENOX1 and myasthenia gravis: Few cases of familial autoimmune MG have been reported: a family with parental consanguinity and five of 10 siblings affected by late-onset autoimmune MG [58], a Hungarian family where nine members from two generations developed MG [6], an Italian-American family with 5 children affected by early-onset MG linked to a variant in the ecto-NADH oxidase 1 gene (ENOX1) [6].