PTX3 and glioblastoma: Based on the ceRNA hypothesis, the CRNDE gene can competitively bind to mir-9-5p, thus increasing the transcription levels of PTX3, MMP9, and STX1A regulated by mir-9-5p, thus affecting the JAK-STAT signaling pathway, apoptosis, and cytokine-cytokine receptor interaction pathways, and promoting the occurrence and development of GBM.