The PSS-associated thrombocytopenia group had significantly elevated levels of IL-8 (196.5 ± 73.4 vs. 137.2 ± 52.9, p = 0.033) and IL-1β (158.5 ± 23.6 vs.130.8 ± 38.7, p = 0.047) compared to the pSS without thrombocytopenia group. This evidence concerns the gene CXCL8 and Thrombocytopenia.