According to the expression level of Linc-KLIH and KRT19 in HCC cell lines, we defined Huh7 and MHCC-97H as KRT19-positive cells, Hep3B as KRT19-negative cells to further explore whether or not Linc-KILH participate in the physiology function of KRT19 in HCC cells. The gene discussed is KRT19; the disease is hepatocellular carcinoma.