KEGG based analysis revealed the over-expressed genes were mainly involved in ferroptosis, hypoxia-inducible factor (HIF)-1 signaling pathway, synthesis of microRNAs in cancer cells, IL-17 signaling pathway, central carbon metabolism in cancer cells, bladder cancer, human cytomegalovirus infection and mTOR signaling pathway (Figure 1 and Table S3). The gene discussed is IL17A; the disease is urinary bladder carcinoma.