Gene set enrichment analyses (GSEA) revealed the majority of the novel ferroptosis-related lncRNAs prognostic signature regulated immune and tumor-related pathways such as primary immunodeficiency, natural killer cell mediated cytotoxicity, T/B cell receptor signaling pathway, FC gamma R mediated phagocytosis, homologous recombination, notch signaling pathway, acute myeloid leukemia, colorectal cancer, and jak stat signaling pathway (Figure 6) and (Table S6). This evidence concerns the gene TBXT and neoplasm.