CGAS and autoimmune disease: In addition to mediating autoimmune diseases, deregulation of cGAS is associated with other pathological processes, such as tumor and cellular senescence.48–51 miR-23a has been reported to be upregulated during skin aging and to accelerate senescence, whereas the potential molecular mechanisms of miR-23a/b in the initiation and progression of cellular senescence remain largely unknown.52,53 Thus, future studies are needed to delineate whether miR-23a/b contribute to other cGAS-related diseases and determine the effectiveness of miR-23a/b for the treatment of these diseases.