We compared this metabolic risk model with other metabolic signatures in previous studies and found that PAFAH1B3 is a good prognostic gene in myelogenous leukemia26 while LPCAT1 is a risky prognostic gene in hepatocellular carcinoma27, which has the same function in colon cancer. Here, PAFAH1B3 is linked to malignant colon neoplasm.