MYCN and neuroblastoma: We also observed genes previously associated with 17q21-ter gain in neuroblastoma, such as TBX226, PPMD127, JMJD614, and BIRC528 being differentially expressed in 17q21-ter gain patients (Supplementary Fig. 1a), whereas MYCN mRNA expression associated with MYCN-amplification (Supplementary Fig. 1b) but not 17q21-ter gain (Supplementary Fig. 1a).