At the same time, tumor cells release chemoattractant proteins that recruit TAMs, such as CCL2, CSF-1, granulocyte–macrophage colony stimulating factor (GM-CSF), hepatocyte growth factor or scatter factor (HGF/SF), stroma-derived factor 1 (SDF-1), and glial cell-derived neurotrophic factor (GDNF). The gene discussed is GDNF; the disease is neoplasm.