The use of stimulator of interferon gene (STING) agonists can also be a solution, as STING has shown to increase TAM production of IFN, re-educating TAMs into a pro-inflammatory phenotype, as well as to recruit and activate T cells in murine models of GBM [209] and non-small cell lung cancer [210]. The gene discussed is STING1; the disease is glioblastoma.