In line with our observation that miR-34a inhibits the function of the RTK, p53 and Rb networks, we found that over-expression of miR-34a inhibits the proliferation of all established glioblastoma cell lines that we have tested, A172, LN229 and T98G, albeit to varying degrees (Fig. 2). The gene discussed is TP53; the disease is glioblastoma.