Several differentially expressed genes between the two trajectories (CTSG, PRC1, DEFA4, KIF15, TCEAL9, HMMR, CEP55, and AZU1) were overexpressed in patients with severe viral infection, but not in those with non-severe viral infection compared to HCs (Figures 5J–5K, Figures S4E and S4F). Here, AZU1 is linked to viral infectious disease.