Several cytokines and chemokines, such as IL-1 beta, IL-2, IL-4, IL-6, IL-8, IL-17, IL-22, Tumor Necrosis Factor (TNF) alpha, interferon (IFN) gamma, granulocyte colony-stimulating factor, IFN-gamma induced protein 10 and monocyte chemoattractant protein 1, might additionally play a role in the pathogenesis of COVID-19, especially for the severe form of the disease [29–34]. This evidence concerns the gene IL1B and COVID-19.